Plasma vs. Urine Analysis Plasma is traditionally used to assess the status of essential AA while urine analysis provides more information regarding AA wasting and aberrant metabolism associated with co-factor insufficiencies.
Plasma amino acid nutritional testing measures what is being transported at the time of sampling. The specimen should be collected after an overnight fast to reduce the influence of dietary protein.
Abnormalities are deduced by comparison of measured levels with an established reference range. The hour urine amino acid analysis has the highest probability of detecting abnormalities if renal function is normal.
The hour test indicates what is high and low over the course of a day, reflects blood and tissue amino acid pools, and is not affected by circadian rhythm. Healthy kidneys efficiently conserve essential amino acids.
Therefore, urine levels of amino acids decrease first and tend to give an earlier indication of inadequacy than do plasma levels. A first morning void urine FMV amino acid analysis, with results normalized per gram creatinine, provides an alternative when a complete hour collection is not a viable option. The FMV analysis is excellent for identification of marked abnormalities, particularly with respect to gastrointestinal health, inherited disorders in amino acid metabolism and renal function, and can be used for protein challenge testing.
For nutritional testing to address your patients' symptoms, reach out to Doctor's Data. We use cookies and similar tools across our websites to improve their performance and enhance your user experience. Learn more about our Cookies Policy and click I understand , to hide this message. Urine Amino Acids Amino acid AA nutritional testing aids in the identification of dietary protein adequacy and amino acid balance, gastrointestinal dysfunctions, forms of protein intolerance, vitamin and mineral deficiencies, renal and hepatic dysfunction, psychiatric abnormalities, susceptibility to inflammatory response and oxidative stress, reduced detoxification capacity and many other inherent and acquired disorders in AA metabolism.
It is common for some of each kind to be found in the urine. Increased levels of individual amino acids can be a sign of a problem with metabolism. The values below represent normal ranges in 24 hours urine for adults. Aspartic acid : 5 to Phenylalanine : 1 to 5. Normal value ranges may vary slightly among different laboratories. Talk to your provider about the meaning of your specific test results. The examples above show the common measurements for results for these tests.
Some laboratories use different measurements or may test different specimens. Screening infants for increased levels of amino acids can help detect problems with metabolism. Early treatment for these conditions may prevent complications in the future. Search Close. Create Account.
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